NFL Vegas Odds, Betting Lines, and Point Spreads provided by VegasInsider. com, along with more pro football information for your sports gaming and betting. NFL odds and spreads for the latest NFL games. NFL Odds: Week 1 .. Betting on the favorite means the team must win by at least fourteen points to cover the. NFL Odds - BOOKMAKER. PM EDT VIEW FUTURES ODDS CFB Week 1: Alabama Crimson Tide-Florida State Seminoles Picks Against the Spread. Thu, Sep 7.